American Statistical Association
New York City
Metropolitan Area Chapter

Mailman School of Public Health
Columbia University
Department of Biostatistics Colloquium



REVISITING COMPETING RISKS DATA

by

Prof. Jason Fine
Department of Biostatistics
University of North Carolina - Chapel Hill


Abstract

Competing risks are classically summarized by cause specific hazards and the cumulative incidence function. To obtain a full understanding of the data, these identifiable quantities should be viewed simultaneously for all possible events. Another available quantity is the conditional probability of a competing risk, which is the probability of failure from a particular cause given that no other competing event has occurred. When one event is of a particular interest, this quantity provides useful information, as it displays a probability adjusted for the other events. However, the use of the conditional probability has been limited due to the lack of a regression modelling strategy. I will present such regression model taking a functional view of the competing risks data, which treats such data as high dimensional temporal data. Insight gained from this methodology is illustrated using a dataset on patients suffering from monoclonal gammopathty of unknown significance. The focus throughout the talk will be the clear definition of competing risks endpoints and the proper interpretation of results from the multiple analyses, which may appear discrepant and difficult to synthesize.


Date: Thursday, March 12, 2009
Time: 4:00 - 5:00 P.M.
Location: Mailman School of Public Health
Department of Biostatistics
722 West 168th Street
Biostatistics Computer Lab
6th Floor - Room 656
New York, New York

RESERVATIONS ARE NOT REQUIRED

Refreshments will be served at 3:30 P.M. in the
Biostatistics Conference Room (R627).


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