American Statistical Association
New York City
Metropolitan Area Chapter

Memorial Sloan-Kettering Cancer Center
Biostatistics Seminar



Andrew Vickers, D.Phil.
Department of Epidemiology and Biostatistics
Memorial Sloan-Kettering Cancer Center

NET RECLASSIFICATION IMPROVEMENT:
A HIGHLY POPULAR, BUT INVALID
METRIC FOR PREDICTIVE VALUE

The Net Reclassification Improvement (NRI) was developed by Pencina and colleagues in 2008. The original paper has been cited close to 2000 times. I will discuss two recent papers demonstrating that it is an invalid statistic.