American Statistical Association
New York City
Metropolitan Area Chapter

Memorial Sloan-Kettering Cancer Center
Biostatistics Seminar



Iuliana Ionita-Laza
Department of Biostatistics
Columbia University

STATISTICAL METHODS FOR NEXT-GENERATION SEQUENCING DATA

Rapid advances in sequencing technologies set the stage for large-scale medical sequencing efforts to assess the importance of rare variants in complex diseases. The low frequency and expected large number of such variants pose difficulties for the analysis of these data. We discuss several statistical strategies for association testing with rare variants, and show applications to a study on autism. Implications to study designs will also be discussed.


Date: Wednesday, January 26, 2011
Time: 4:00 - 5:00 P.M.
Location: Memorial Sloan-Kettering Cancer Center
Department of Epidemiology and Biostatistics
307 East 63rd Street
(between First and Second Avenues)
Room 331
New York, New York
Note: To gain access to the building, please follow the directions by the telephone in the foyer.

RESERVATIONS ARE NOT REQUIRED


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