American Statistical Association
New York City
Metropolitan Area Chapter

Memorial Sloan-Kettering Cancer Center
Biostatistics Seminar


Keith A. Baggerly, Ph.D.
Department of Bioinformatics and Computational Biology
Division of Quantitative Sciences
The University of Texas MD Anderson Cancer Center

WHEN IS REPRODUCIBILITY AN ETHICAL ISSUE?
GENOMICS, PERSONALIZED MEDICINE, AND HUMAN ERROR

Modern high-throughput biological assays let us ask detailed questions about how diseases operate, and promise to let us personalize therapy. Careful data processing is essential, because our intuition about what the answers "should" look like is very poor when we have to juggle thousands of things at once. When documentation of such processing is absent, we must apply "forensic bioinformatics" to work from the raw data and reported results to infer what the methods must have been. We will present several case studies where simple errors may have put patients at risk. This work has been covered in both the scientific and lay press, and has prompted several journals to revisit the types of information that must accompany publications. We discuss steps we take to avoid such errors, and lessons that can be applied to large data sets more broadly.


Please note the change in time and location from that of the usual seminars.
Date: Wednesday, February 19, 2014
Time: 11:00 A.M.- 12:00 P.M.
Location: Memorial Sloan-Kettering Cancer Center
Zuckerman Research Center
415 East 68th Street
Room Z-105
New York, New York

RESERVATIONS ARE NOT REQUIRED


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