American Statistical Association
New York City
Metropolitan Area Chapter

Memorial Sloan-Kettering Cancer Center
Biostatistics Seminar


Ann G. Zauber, Ph.D.
Associate Attending Biostatistician
Memorial Sloan-Kettering Cancer Center

DECISION ANALYSIS OF COLORECTAL CANCER SCREENING TESTS
BY AGE TO BEGIN, AGE TO END, AND SCREENING INTERVALS:
REPORT TO THE UNITED STATES PREVENTIVE SERVICES TASK FORCE
FROM THE CANCER INTERVENTION AND
SURVEILLANCE MODELING NETWORK (CISNET) FOR 2007

In 2002, the United States Preventive Task Force (USPSTF) concluded that there was sufficient evidence to support colorectal cancer screening in the average risk population beginning at age 50 but there was not sufficient evidence to recommend one colorectal cancer-screening test over another. In 2007, the USPSTF scheduled to review their 2002 recommendations and requested a decision analysis of age to begin screening, age to end, and intervals of screening for multiple colorectal cancer screening tests. Two microsimulation modeling groups (MISCAN and SimCRC) from the Cancer Intervention and Surveillance Network (CISNET) provided a comparative modeling analysis of these questions to the Task Force to inform their decision. Previous task force recommendations have been informed by an evidence review; this is the first time that the Task Force has also utilized a decision analysis. I will describe the microsimulation models, the inputs for the decision analysis, the comparative modeling, and the results. The USPSTF decision is currently under review.


Date: Wednesday, March 26, 2008
Time: 4:00 P.M. - 5:00 P.M.
Location: Memorial Sloan-Kettering Cancer Center
Department of Epidemiology and Biostatistics
307 East 63rd Street
(between First and Second Avenues)
3rd Floor Conference Room
New York, New York
Note: To gain access to the building, please follow the directions by the telephone in the foyer.

RESERVATIONS ARE NOT REQUIRED


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