American Statistical Association
New York City
Metropolitan Area Chapter

Memorial Sloan-Kettering Cancer Center
Biostatistics Seminar


Yuelin Li, Ph.D.
Assistant Attending Behavioral Scientist
Memorial Sloan-Kettering Cancer Center

DISCOVERING LATENT GROWTH TRAJECTORIES
OF A BIOMARKER AND LINK THEM TO A SURVIVAL OUTCOME:
SIMPLIFICATION OR OVEREXTRACTION?

The topic of my talk is Growth Mixture Modeling, a method to discover latent growth trajectories in longitudinal outcomes (e.g., Prostate-Specific Antigen test) and link these latent growth curves with an outcome of interest (e.g., survival without PCa). The advantages of GMM over mixed-effects models in longitudinal data analysis will be discussed. Several applications of GMM will be summarized, with a focus on McCulloch et al's (2002) study on linking longitudinal changes in PSA with survival. I will briefly describe how to carry out a similar analysis with a binary outcome (not survival) using Mplus.


Date: Wednesday, April 23, 2008
Time: 4:00 P.M. - 5:00 P.M.
Location: Memorial Sloan-Kettering Cancer Center
Department of Epidemiology and Biostatistics
307 East 63rd Street
(between First and Second Avenues)
3rd Floor Conference Room
New York, New York
Note: To gain access to the building, please follow the directions by the telephone in the foyer.

RESERVATIONS ARE NOT REQUIRED


Home Page | Chapter News | Chapter Officers | Chapter Events
Other Metro Area Events | ASA National Home Page | Links To Other Websites
NYC ASA Chapter Constitution | NYC ASA Chapter By-Laws

Copyright © 2008 by New York City Metropolitan Area Chapter of the ASA
Designed and maintained by Cynthia Scherer
Send questions or comments to nycasa@mindspring.com