American Statistical Association
New York City
Metropolitan Area Chapter

Memorial Sloan Kettering Cancer Center
Department of Epidemiology and Biostatistics
Biostatistics Seminar Series


Mithat Gönen, Ph.D.
Department of Epidemiology and Biostatistics
Memorial Sloan Kettering Cancer Center

INTERRUPTED TIME SERIES DESIGN FOR COMPARATIVE EFFICACY TRIALS
WITH AN APPLICATION TO THE USE OF
A CARE BUNDLE TO REDUCE SURGICAL SITE INFECTIONS

Interrupted Time Series design has been proposed as a way to compare treatments which require large-scale implementation and renders randomization infeasible. Each treatment is implemented in blocks of time where all eligible patients are considered to have enrolled in that treatment arm. Comparisons across treatments are carried out as comparisons across these blocks of time with adjustments to time trends and possible autocorrelation of outcomes. We applied this method to a trial evaluating the ability of a care bundle to reduce surgical site infections in patients undergoing colon surgery at MSK.

This is joint work with Martin Weiser of the Department of Surgery.


Date: Wednesday, April 26, 2017
Time: 4:00 - 5:00 P.M.
Location: Memorial Sloan Kettering Cancer Center
Department of Epidemiology and Biostatistics
485 Lexington Avenue
(Between 46th & 47th Streets)
2nd Floor, Conference Room B
New York, New York

**Outside visitors please email celeat@mskcc.org for building access.
You must be on the security list to enter the floor.

The World of Statistics
Home Page | Chapter News | Chapter Officers | Chapter Events
Other Metro Area Events | ASA National Home Page | Links To Other Websites
NYC ASA Chapter Constitution | NYC ASA Chapter By-Laws

Page last modified on April 26, 2017
Copyright © 1998-2017 by New York City Metropolitan Area Chapter of the ASA
Designed and maintained by Cynthia Scherer
Send questions or comments to admin@nycasa.org