American Statistical Association
New York City
Metropolitan Area Chapter

Memorial Sloan Kettering Cancer Center
Department of Epidemiology and Biostatistics
Biostatistics Seminar Series


Patrick Heagerty, Ph.D.
Chair, Department of Biostatistics
University of Washington

RANK-BASED AND RISK-BASED MEASURES TO EVALUATE BIOMARKERS
AS PREDICTORS OF INCIDENT CASES AND CONNECTION TO INFORMATION THEORY

In many biomedical applications a primary goal is to predict incident or future cases and appropriate descriptive measures that characterize predictive potential or incremental value are needed. We first review non-parametric methods proposed for incident time-dependent accuracy (Zheng and Heagerty, 2005; Saha and Heagerty, 2013) and then overview extensions of integrated discrimination index (IDI) that are appropriate for hazard models (Liang and Heagerty, 2017). New methods are connected to information theory-based criteria for model choice. Non-parametric estimation is outlined and application to benchmark data sets is presented to illustrate the methodology.


Date: Wednesday, May 29, 2019
Time: 4:00 - 5:00 P.M.
Location: Memorial Sloan Kettering Cancer Center
Department of Epidemiology and Biostatistics
485 Lexington Avenue
(Between 46th & 47th Streets)
2nd Floor, Conference Room B
New York, New York

**Outside visitors please email koppenar@mskcc.org for building access. You must be on the security list to enter the floor.

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