American Statistical Association
New York City
Metropolitan Area Chapter

Memorial Sloan-Kettering Cancer Center
Biostatistics Seminar


Hongyu Zhao, Ph.D.
Professor
Yale School of Public Health

INCORPORATING PRIOR BIOLOGICAL KNOWLEDGE
IN GENOME-WIDE ASSOCIATION STUDIES

The last three years have seen great successes in Genome-Wide Association Studies (GWAS) which have identified numerous genetic variants underlying complex traits. The analysis and interpretation of data from GWAS presents great statistical and computational challenges, especially after the initial discoveries of variants carrying relatively large effects. Although various statistical approaches have been or are being developed to better analyze GWAS data, it has become apparent that the incorporation of information from prior studies and other sources is indispensable. In this presentation, we discuss our recently developed statistical methods and bioinformatics tools that are designed to more effectively integrate diverse types of prior biological information in analyzing GWAS data. The usefulness of these methods will be illustrated through their applications to some recent large-scale GWAS data.

This is joint work with Iryna Lobach, David Ballard, Ji Young Lee, and Judy Cho.


Date: Wednesday, October 1, 2008
Time: 4:00 P.M. - 5:00 P.M.
Location: Memorial Sloan-Kettering Cancer Center
Department of Epidemiology and Biostatistics
307 East 63rd Street
(between First and Second Avenues)
3rd Floor Conference Room
New York, New York
Note: To gain access to the building, please follow the directions by the telephone in the foyer.

RESERVATIONS ARE NOT REQUIRED


Home Page | Chapter News | Chapter Officers | Chapter Events
Other Metro Area Events | ASA National Home Page | Links To Other Websites
NYC ASA Chapter Constitution | NYC ASA Chapter By-Laws

Copyright © 2008 by New York City Metropolitan Area Chapter of the ASA
Designed and maintained by Cynthia Scherer
Send questions or comments to nycasa@mindspring.com