American Statistical Association
New York City
Metropolitan Area Chapter

Memorial Sloan-Kettering Cancer Center
Biostatistics Seminar



Sujata Patil, Ph.D.
Department of Epidemiology & Biostatistics
Memorial Sloan-Kettering Cancer Center

STATISTICAL CHALLENGES IN DEFINING SATISFACTORY
OR UNSATISFACTORY SERUM TUMOR MARKER DECLINE
DURING CHEMOTHERAPY FOR GERM CELL TUMORS

Serum tumor markers such as alphafetoprotein (AFP) and human chorionic gonadotropin (HCG) have been shown to be important in the diagnosis and management of patients with germ cell tumors. In many analyses, the rate of decline of these two markers during therapy is categorized as satisfactory or unsatisfactory based on half-life calculations and patient-specific linear regressions. There are challenges in using such categorizations. In this talk, I will talk about how variability in patient-specific half-life calculations can be adjusted for in analysis using a measurement error approach.


Date: Wednesday, November 20, 2013
Time: 4:00 - 5:00 P.M.
Location: Memorial Sloan-Kettering Cancer Center
Department of Epidemiology and Biostatistics
307 East 63rd Street
(between First and Second Avenues)
3rd Floor Conference Room
New York, New York
Note: To gain access to the building, please follow the directions by the telephone in the foyer.

RESERVATIONS ARE NOT REQUIRED


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